500 error with Nginx and WordPress pretty permalinks

Ran into a 500 issue when running Nginx and WP together and setting pretty permalinks. I've been trying a bunch of different methods from Google but none seems to help. Config - ``` server { listen 80; root /var/www/mydomain.com/public_html; index index.php index.html index.htm; server_name .mydomain.com; location / { try_files $uri $uri/ /index.php?$args; } location ~ \.php$ { try_files $uri =404; fastcgi_pass unix:/var/run/php5-fpm.sock; fastcgi_index index.php; include fastcgi_params; } } ``` All files load perfectly well, and the pages work if using the default permalinks setting. Strange thing is, if I check the network log I first see a 200 OK being received, then immediately followed by a 500. Any ideas? Edit: Setting to close as I'm switching to Apache instead. Will mark correct answer as it seems to have helped others.